CNBC 2025 · #34 of 50

Missouri

Moderate
Overall score
77 /100

Rank: #34 of 50

Category breakdown

All 10 CNBC categories — score out of category max, rank among 50 states.

Economy #37 204/445
Infrastructure #23 215/405
Workforce #48 112/335
Cost of Doing Business #6 209/295
Business Friendliness #29 137/270
Quality of Life #39 99/265
Technology & Innovation #28 124/255
Education #8 65/110
Access to Capital #26 28/60
Cost of Living #4 45/60

CNBC methodology — 10 categories, 2,500 points max

Founder Snapshot

Lite operational context for Missouri — what to know before operating here. Sourced public facts, separate from CNBC scores.

Tax posture

Missouri corporate income tax is 4%. Personal income tax tops out at 4.7% (2025). No statewide franchise tax for most LLCs.

Source: Missouri Department of Revenue

Business registration

Register entities through the Missouri Secretary of State Business Services.

Source: Missouri Secretary of State

Compliance calendar

Annual registration reports are due by the end of the registration anniversary month.

Source: Missouri SOS — Annual Registration

Multi-state heads-up

If you operate outside Missouri or hire remotely — informational, not legal advice.

Remote sales & economic nexus

Remote sellers must collect Missouri use tax once economic nexus thresholds are exceeded.

Source: Missouri DOR — Sales & Use Tax

Remote employees & payroll

Missouri employers must register for withholding and unemployment insurance.

Source: Missouri DOR — Withholding

Also applies across state lines

Regulatory Pulse

Recent regulatory changes in Missouri — sourced public updates for founders operating here.